1887

Abstract

SUMMARY: Drug resistant mutants of the slime mould useful for mitotic genetic analysis have been studied. Mutations to acriflavin resistance are recessive and have been assigned to two genes () located in different linkage groups. One of these () confers resistance to the unrelated compounds methanol and thiabendazole. Ability to grow axenically (in the absence of bacteria) is determined by genes on two linkage groups, one carrying and the other an established temperature sensitive mutation. Preliminary results for two linkage groups show that the sequence of genes on a linkage group can be determined by analysis of homozygous drug resistant diploids, obtained by drug selection from diploids heterozygous for recessive drug resistance markers.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-84-1-59
1974-09-01
2020-01-21
Loading full text...

Full text loading...

http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-84-1-59
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error