RT Journal Article SR Electronic(1) A1 van Hartingsveldt, J. A1 Stouthamer, A. H.YR 1974 T1 Properties of a Mutant of Pseudomonas aeruginosa Affected in Aerobic Growth JF Microbiology, VO 83 IS 2 SP 303 OP 310 DO https://doi.org/10.1099/00221287-83-2-303 PB Microbiology Society, SN 1465-2080, AB SUMMARY: mutant of Pseudomonas aeruginosa affected in aerobic growth (aer) was partially characterized. When shifted from anaerobic to aerobic conditions mutant bacteria continued growth. During this aerobic growth after the shift the mutant bacteria differed from the wild type in some respects. First, the concentration of intracellular haem decreased gradually, whereas coproporphyrin was released into the culture fluid. Apparently haem synthesis is blocked under aerobic conditions, so oxygen uptake by the mutant culture did not increase as much as by the wild type after a shift. Second, the anaerobic nitrate-respiratory system of the mutant exhibited an altered sensitivity to oxygen after a shift to aerobiosis. Nitrate and nitrite reduction were not inhibited and nitrite reductase synthesis was not repressed by oxygen. P/O values determined in intact bacteria showed that respiration with oxygen was still coupled to ATP formation in the mutant., UL https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-83-2-303