SUMMARY: Haemin was found in all specimens of purified preparations of Rous I, Duran-Reynals B, D and V, Fujinami, and MH2 viruses, and also in macromolecular preparations from non-filterable fowl sarcomas and normal fowl tissues. The amounts were not constant in different batches of Rous I, and it was shown that this virus would strongly adsorb pure haemin from solution. It is suggested that most, probably all, of the haemin encountered in these preparations was derived from the host blood. Adsorbed haemin had no effect on the oxidative destruction of the virus, but slightly altered its physical properties.


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