1887

Abstract

SUMMARY: Roper’s technique for the production in filamentous fungi of strains with heterozygous diploid nuclei in their hyphae (Roper, 1952) has been applied successfully to , in which a sexual cycle does not occur. The diploids, heterozygous for known markers, give origin to new strains, most still diploid, homozygous for some or all of the markers and therefore associating or recombining in all possible ways the properties of the two strains from which the diploid was formed. Genetic recombination has thus been achieved in a filamentous fungus without a normal sexual cycle. Imperfect fungi are now open to genetic investigation. Deliberate ‘breeding’ of strains has become a practical proposition in industrial fermentations based on these fungi.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-8-1-198
1953-03-01
2024-12-06
Loading full text...

Full text loading...

/deliver/fulltext/micro/8/1/mic-8-1-198.html?itemId=/content/journal/micro/10.1099/00221287-8-1-198&mimeType=html&fmt=ahah

References

  1. Forbes E. 1952; The use of SO2 for selecting auxotrophs in filamentous fungi. Microbial Genetics Bull 6:26
    [Google Scholar]
  2. Gossop G. H., Yuill E., Yuill J. L. 1940; Heterogeneous fructifications in Aspergillus. Trans. Brit, mycol. Soc 24:337
    [Google Scholar]
  3. Pontecorvo G. 1947; Genetic systems based on heterokaryosis. Cold Spr. Harb. Sym. quant. Biol 11:193
    [Google Scholar]
  4. Pontecorvo G. 1952a; Non-random distribution of multiple mitotic crossing-over among nuclei of heterozygous diploid Aspergillus. Nature, Land 170:204
    [Google Scholar]
  5. Pontecorvo G. 1952b; The genetics of Aspergillus nidulans. Advanc. Genet 5: (in the press)
    [Google Scholar]
  6. Pontecorvo G., Roper J. A. 1952a; Genetic analysis without sexual reproduction by means of polyploidy in Aspergillus nidulans. J. gen. Microbiol 6:vii
    [Google Scholar]
  7. Pontecorvo G., Roper J. A. 1952b; Diploids and mitotic recombination. Advanc. Genet 5: (in the press)
    [Google Scholar]
  8. Roper J. A. 1952; Production of heterozygous diploids in filamentous fungi. Experientia 8:14
    [Google Scholar]
  9. Stern C. 1936; Somatic crossing-over and segregation in Drosophila melanogaster. Genetics 21:625
    [Google Scholar]
  10. Yuill E. 1950; The numbers of nuclei in conidia of Aspergilli. Trans. Brit, mycol. Soc 33:324
    [Google Scholar]
/content/journal/micro/10.1099/00221287-8-1-198
Loading
/content/journal/micro/10.1099/00221287-8-1-198
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error