Summary: Conidia of transported the acidic amino acids and some basic and neutral amino acids at very low rates. During germination the rates of transport of these amino acids increased. The rate of permease synthesis/litre of culture increased during germination, reaching a maximum soon after onset of exponential growth; during subsequent growth the rate of synthesis (per litre of culture) was constant.

The activity of the acidic amino acid permease, measured in germinated conidia, varied with the nitrogen source in the germination medium. An analysis of the intracellular pool of amino acids has shown no clear correlation between activity of the permease and the intracellular concentration of any amino acid.

The acidic amino-acid permease of is probably regulated by ammonia from within the organism and this regulation is achieved by both inhibition and repression.


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