1887

Abstract

SUMMARY: Cold-sensitive mutants of bacteria are a source of strains defective in the assembly of ribosomes (Guthrie, Nashimoto & Nomura, 1969; Tai, Kessler & Ingraham, 1969). A study of cold-sensitive mutants in was undertaken in the hope that it would provide ribosomal mutants. Cold-sensitive () mutants were isolated, and when crossed with wild-type the majority of 32 mutants tested segregated as single-gene mutations.

One mutant, , showed non-Mendelian segregation of its cold-sensitive character in such a cross. This paper presents further results demonstrating the extranuclear inheritance of .

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-78-2-379
1973-10-01
2021-10-21
Loading full text...

Full text loading...

/deliver/fulltext/micro/78/2/mic-78-2-379.html?itemId=/content/journal/micro/10.1099/00221287-78-2-379&mimeType=html&fmt=ahah

References

  1. Alderson M., Hartley M. J. 1969; Specificity for spontaneous and induced mutation at several gene loci in Pseudomonas aeruginosa.. Mutation Research 8:255–264
    [Google Scholar]
  2. Guthrie C., Nashimoto H., Nomura M. 1969; Structure and function of Pseudomonas aeruginosa. coli ribosomes. VIII. Cold- sensitive mutants defective in ribosome assembly.. Proceedings of the National Academy of Sciences of the United States of America 57:384–391
    [Google Scholar]
  3. Handley L., Caten C. E. 1973Heredity (in the Press)
  4. Jinks J. L. 1964Extrachromosomal inheritance Englewood Cliffs, New Jersey: Prentice-Hall.;
  5. Pontecorvo G., Roper J. A., Hemmons L. M., Macdonald K. D., Bufton A. W. J. 1953; !The genetics of Pseudomonas aeruginosa.. Advances in Genetics 5:141–238
    [Google Scholar]
  6. Rowlands R. T., Turner G. 1973; Nuclear and extranuclear inheritance of oligomycin-resistance in Pseudomonas aeruginosa.. Journal of General Microbiology 75:xix
    [Google Scholar]
  7. Tai P.-C., Kessler D. P., Ingraham J. 1969; Cold-sensitive mutations in Salmonella typhimurium which affect ribosome synthesis.. Journal of Bacteriology 97:1298–1304
    [Google Scholar]
  8. Woodward V. W., De Zeeuw J. R., Srb A. M. 1954; The separation and isolation of particular biochemical mutants of Neurospora by differential germination of conidia followed by filtration and selective plating.. Proceedings of the National Academy of Sciences of the United States of America 40:192–200
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-78-2-379
Loading
/content/journal/micro/10.1099/00221287-78-2-379
Loading

Data & Media loading...

Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error