1887

Abstract

SUMMARY: The lipopolysaccharides from fifteen strains of used for serotyping have been isolated and analysed. They all contained heptose, glucose, rhamnose, glucosamine, galactosamine, 2-keto-3-deoxyoctonic acid and alanine. Many of them contained additional sugars and amino compounds, some of which have been shown to be amino sugars. Their composition and structure suggested the existence of a common region of low molecular weight in all the lipopolysaccharides. They could be classified by their chemistry and that of their degradation products into twelve chemogroups, nine of which contained one serotype and three of which contained two serotypes. All the lipopolysaccharides contained the same fatty acids, 3-OH 10:0, 2-OH 12:0, 3-OH 12:0 and 12:0. The isolated lipopolysaccharides reacted with the homologous Habs type antisera. The serological specificity was limited to the high molecular weight regions thought to correspond to side chains.

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/content/journal/micro/10.1099/00221287-78-2-305
1973-10-01
2021-08-06
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