Summary: The prophage ϕC31 was shown to be a genetic determinant of lysogeny in A3(2). In mapping experiments with strains cured and relysogenized with mutant phages the prophage was located on the Streptomyces chromosome.

Allele ratios of non-selected markers for crosses between lysogenic and non-lysogenic derivatives of A3(2) differ strikingly from those of crosses between non-lysogenic parents. It is suggested that these differences are due to the loss of certain recombinant classes containing the complete chromosome of the non-lysogenic parent and a fragment from the lysogenic one, as a result of zygotic induction.


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