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SUMMARY: In an attempt to locate the antigens associated with protection against foot-rot the fine structure of Fusiformis nodosus and the interaction between the organism and specific antiserum obtained from vaccinated animals were studied.
The high titres of circulating agglutinin associated with immunity were shown to be due to the interaction between antibodies and pili. These observations are discussed in relation to the structure and pathogenicity of other Gram-negative organisms.
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