The Sensitivity of Suppressed and Unsuppressed Strains of to Chemical Agents which Induce Filamentation Free

Abstract

Summary: The sensitivities of strains of to the filament inducing agents nalidixic acid, gentian violet, crystal violet and penicillin were examined. The strains used included those in which the gene is suppressed by and as well as strains in which the Lon phenotype is expressed. The sensitivity of the bacteria to agents which act on DNA was reduced when was suppressed, but the extent of the decrease in sensitivity was dependent on the mechanism by which suppression was effected. Sensitivity to penicillin, on the other hand, was reduced only in the strain and by a mechanism which appears to be independent of the direct suppression of model to account for these results indicates possible sites at which the and genes are expressed.

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/content/journal/micro/10.1099/00221287-76-2-429
1973-06-01
2024-03-29
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