%0 Journal Article %A Sherratt, D. J. %A Collins, J. F. %T Analysis by Transformation of the Penicillinase System in Bacillus licheniformis %D 1973 %J Microbiology, %V 76 %N 1 %P 217-230 %@ 1465-2080 %R https://doi.org/10.1099/00221287-76-1-217 %I Microbiology Society, %X Summary: The penicillinase locus is weakly linked to the ilvA and ilvD loci in Bacillus licheniformis. Transformants for these markers include up to 5% of transfor-mants for the penicillinase locus. Penicillinase mutants have been mapped in the structural gene and at least two regulatory genes. One regulatory gene is 90% linked to the structural gene, a second regulatory gene is 50% linked to the first regulatory gene. Another possible regulatory gene is unlinked to the others. Mutations in the first regulatory gene show it has a negative control function; the other regulatory mutations result in defective inducibility though the role of the gene products is not known. A model for the regulation of penicillinase synthesis in this organism is discussed. %U https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-76-1-217