1887

Abstract

SUMMARY: A correlated electron microscopy and biochemical study of the effects of staphylococcal α-toxin on rabbit erythrocyte membrane structure has been carried out. Using several criteria, no evidence was obtained for the involvement of a proteolytic mechanism in the mode of action of this toxin.

After toxin treatment, ghosts examined by freeze-etching showed changes in micromorphology consistent with a hydrophobic interaction between toxin and membrane.

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/content/journal/micro/10.1099/00221287-75-2-321
1973-04-01
2021-08-02
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