1887

Abstract

SUMMARY: On storage, pigmented (orange or yellow) strains of produce non-pigmented variants which are more susceptible to desiccation and to linoleic acid than are the corresponding wild strains. The association of these properties could explain why most staphylococci isolated from clinical sources are pigmented, although the pigmented character is lost at high frequency

The genes determining these properties are not borne by a typical plasmid since the capacity to produce pigment was not transducible, and no covalently closed circular DNA was detected in lysates of three pigmented strains. There was an apparent reduction in cellular DNA of 30 to 40% associated with the loss of these genes; however, DNA/DNA hybridization could not distinguish between total cellular DNA from a pigmented strain (PAR5) and that isolated from the corresponding non-pigmented variant.

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/content/journal/micro/10.1099/00221287-75-2-259
1973-04-01
2022-01-18
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References

  1. Altenbern R. A. 1967; Genetic studies of pigmentation of Staphylococcus aureus. Canadian Journal of Microbiology 13:389–395
    [Google Scholar]
  2. Denhardt D. T. 1966; A membrane-filter technique for the detection of complementary DNA. Biochemical and Biophysical Research Communications 23:641–646
    [Google Scholar]
  3. Doudoroff M. 1936; Association of characters among dissociates from Staphylococcus aureus. Proceedings of the Society for Experimental Biology and Medicine 34:216–217
    [Google Scholar]
  4. Giles K. W., Myers A. 1965; An improved diphenylamine method for the estimation of deoxyribonucleic acid. Nature, London 205:93
    [Google Scholar]
  5. Grinsted J., Saunders J. R., Ingram L., Sykes R. B., Richmond M. H. 1972; Properties of an R factor which originated in Pseudomonas aeruginosa 1822. Journal of Bacteriology 110:529–537
    [Google Scholar]
  6. Lacey R. W. 1968; Antibacterial action of human skin. In vivo effect of acetone, alcohol and soap on behaviour of Staphylococcus aureus. British Journal of Experimental Pathology 49:209–215
    [Google Scholar]
  7. Lacey R. W. 1971; Transfer of tetracycline-resistance between strains of Staphyloccocus aureus in mixed cultures. Journal of General Microbiology 69:229–237
    [Google Scholar]
  8. Lacey R. W. 1972; Genetic control in methicillin-resistant strains of Staphylococcus aureus. Journal of Medical Microbiology 5:497–508
    [Google Scholar]
  9. Lacey R. W., Alder V. G., Gillespie W. A. 1970; The survival of Staphylococcus aureus on human skin. An investigation using mixed cultures. British Journal of Experimental Pathology 51:305–313
    [Google Scholar]
  10. Lacey R. W., Grinsted J. 1972; Linkage of fusidic acid-resistance to the penicillinase plasmid in Staphylococcus aureus. Journal of General Microbiology 73:501–508
    [Google Scholar]
  11. Marmur J. 1961; A procedure for the isolation of deoxyribonucleic acid from microorganisms. Journal of Molecular Biology 3:208–218
    [Google Scholar]
  12. Novick R. P., Bouanchaud D. 1971; Extrachromosomal nature of drug resistance in Staphylococcus aureus. Annals of the New York Academy of Sciences 182:279–294
    [Google Scholar]
  13. Pinner M., Voldrich M. 1932; Derivation of Staphylococcus albus, citreus and roseus from Staphylococcus areus. Journal of Infectious Diseases 50:185–202
    [Google Scholar]
  14. Ricketts C. R., Squire J. R., Topley E. 1951; Human skin lipids with particular reference to the self-sterilizing power of the skin. Clinical Science 10:89–112
    [Google Scholar]
  15. Saunders J. R., Grinsted J. 1972; Properties of RP 4, an R factor which originated in Pseudomonas aeruginosa S 8. Journal of Bacteriology 112:690–696
    [Google Scholar]
  16. Servin-Massieu M. 1961; Spontaneous appearance of sectored colonies in Staphyloccus aureus. Journal of Bacteriology 82:316–317
    [Google Scholar]
  17. Willis A. T., Smith J. A., O’Connor J. J. 1966; Properties of some epidemic strains of Staphylococcus aureus. Journal of Pathology and Bacteriology 92:345–358
    [Google Scholar]
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