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SUMMARY: Scanning electron microscopy of intact fixed trophozoites of Toxoplasma gondii showed typical crescent-shaped organisms with clear polar structures. Examination of living organisms exposed to mouse peritoneal macrophages and L-cells and then fixed suggested that phagocytosis is one method of entry of the parasite into both phagocytic cells and those usually considered non-phagocytic. Antibody and accessory factor collapsed the organisms; irregular vacuoles appeared on their surfaces and cytoplasmic contents were extruded.
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