1887

Abstract

Teichoic acids form part of the bacteriophage receptor sites in the walls of several Gram-positive bacteria (Young, 1967; Coyette & Ghuysen, 1968; Chatterjee, 1969). Concanavalin A interacts with teichoic acids that possess α-linked glucosyl or -acetyl-glucosaminyl substituents (Archibald & Coapes, 1971; Reeder & Ekstedt, 1971) and so might be expected to prevent access of bacteriophages to their receptor sites in walls which contain such teichoic acids. We have examined the influence of Concanavalin A on the binding of bacteriophage K (Ralston, Baer, Lieberman & Kreuger, 1957) to strains 3528, A1 and H, the walls of which contain exclusively α, exclusively β- and predominantly β-, with some α-, -acetyl-glucosaminyl substituents respectively (Baddiley, Buchanan, Martin & RajBhandary, 1962; Nathenson & Strominger, 1962; Davison, Baddiley, Hofstad, Losnegard & Oeding, 1964). The action of Concanavalin A on the binding of bacteriophage SP-50 (Foldes & Trautner, 1964) to strains 3610 and w-23, the wall teichoic acids of which contain respectively α- and β-linked glucosyl substituents (Chin, Burger & Glaser, 1966; Doyle & Birdsell, 1972) has also been studied. Additionally we have studied the effect of Concanavalin A on the infection of strains W-23 and 3610 by bacteriophage SP-50 and of strains 3528 and H by the typing bacteriophages 53 and 52A respectively.

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/content/journal/micro/10.1099/00221287-73-3-581
1972-12-01
2021-07-24
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References

  1. Adams M. H. 1959 Bacteriophages pp 450–451 New York: Interscience Publishers Inc.;
    [Google Scholar]
  2. Archibald A. R., Coapes H. E. 1971; The interaction of Concanavalin A with teichoic acids and bacterial cell walls.. Biochemical Journal 123:665–667
    [Google Scholar]
  3. Baddiley J., Buchanan J. G., Martin R. O., RajBhandary U. L. 1962; Teichoic acid from the walls of Staphylococcus aureus h. Location of phosphate and alanine residues.. Biochemical Journal 85:49–55
    [Google Scholar]
  4. Chatterjee A. N. 1969; Use of bacteriophage resistant mutants to study the nature of the bacteriophage receptor site of Staphylococcus aureus.. Journal of Bacteriology 98:519–527
    [Google Scholar]
  5. Chin T., Burger M. M., Glaser L. 1966; Synthesis of teichoic acids. VI. The formation of multiple wall polymers in Bacillus subtilis w-23.. Archives of Biochemistry and Biophysics 116:358–367
    [Google Scholar]
  6. Coyette J., Ghuysen J. M. 1968; Structure of the cell wall of Staphylococcus aureus strain Copenhagen. IX. Teichoic acid and phage absorption.. Biochemistry 7:2385–2389
    [Google Scholar]
  7. Davison A. L., Baddiley J., Hofstad T., Losnegard N., Oeding P. 1964; Teichoic acids in the walls of Staphylococci. Serological investigations on teichoic acids from the walls of Staphylococci.. Nature, London 202:872–874
    [Google Scholar]
  8. Doyle R. J., Birdsell D. C. 1972; Interaction of Concanavalin A with the cell wall of Bacillus subtilis.. Journal of Bacteriology 109:652–658
    [Google Scholar]
  9. Foldes J., Trautner T. A. 1964; Infectious DNA from a newly isolated B. subtilis phage.. Zeitschrift für Vererbungslehre 95:57–65
    [Google Scholar]
  10. Nathenson S. C., Strominger J. L. 1962; Enzymatic synthesis and immunochemistry of N-acetyl-glucosaminyl linkages in teichoic acids of Staphylococcus aureus strains.. Journal of Biological Chemistry 237:3839–3841
    [Google Scholar]
  11. Olson M. O. J., Liener I. E. 1967; Some physical and chemical properties of Concanavalin A, the phytohaemagglutinin of the Jack Bean.. Biochemistry 6:105–111
    [Google Scholar]
  12. Ralston D. J., Baer B. S., Lieberman M., Kreuger A. P. 1957; Lysis-from-without of S. aureus k, by the combined action of phage and virolysin.. Journal of General Physiology 41:343–358
    [Google Scholar]
  13. Reeder W. J., Ekstedt R. D. 1971; Study of the interaction of Concanavalin A with Staphylococcal teichoic acids.. Journal of Immunology 106:334–340
    [Google Scholar]
  14. Young F. E. 1967; Requirement of glucosylated teichoic acid for adsorption of phage in B. subtilis 168.. Proceedings of the National Academy of Sciences of the United States of America 58:2377–2383
    [Google Scholar]
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