
Full text loading...
SUMMARY: Metabolism of Mycobacterium lepraemurium harvested from infected mice was studied using radioisotope tracer techniques. 14C-labelled acetate, fumarate, glycerol, α-ketoglutarate, glutamine and succinate were oxidized and assimilated, but at extremely low rates. Asparagine and glucose were assimilated but not oxidized. These data provide unequivocal evidence for the utilization of exogenous substrates by purified suspensions of M. lepraemurium and indicate the existence of a host-independent aerobic metabolism and an operative tricarboxylic acid cycle.
Article metrics loading...
Full text loading...
References
Data & Media loading...