SUMMARY: The products of several megacinogenic strains of were analysed by starch-gel electrophoresis. All were mixtures of inhibitors, among which megacins A, C and Cx could be distinguished. Several non-inducible megacins were produced in liquid medium and they seemed to be a heterogeneous group which may correspond to ‘megacin B’. The effects of heat and proteolytic enzymes on megacins were investigated and the molecular weights of several megacins were estimated by chromatography using Sephadex G 200. The molecular weight of crude megacin C was about 153000. Strains producing megacins C and Cx could be ‘cured’ by growth at 43°C. Megacins C and Cx were released from the surface of meg organisms by partial digestion of the wall with trypsin or lysozyme.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error