1887

Abstract

SUMMARY: The products of several megacinogenic strains of were analysed by starch-gel electrophoresis. All were mixtures of inhibitors, among which megacins A, C and Cx could be distinguished. Several non-inducible megacins were produced in liquid medium and they seemed to be a heterogeneous group which may correspond to ‘megacin B’. The effects of heat and proteolytic enzymes on megacins were investigated and the molecular weights of several megacins were estimated by chromatography using Sephadex G 200. The molecular weight of crude megacin C was about 153000. Strains producing megacins C and Cx could be ‘cured’ by growth at 43°C. Megacins C and Cx were released from the surface of meg organisms by partial digestion of the wall with trypsin or lysozyme.

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/content/journal/micro/10.1099/00221287-72-3-473
1972-10-01
2022-01-29
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