1887

Abstract

Summary

Anaerobiosis, dinitrophenol and sodium azide decreased catabolite repression of ‐galactosidase caused by glucose in non‐growing ‐12. Anaerobiosis had no effect on the efficiency of exogenous cyclic AMP in stimulating enzyme synthesis. In contrast, dinitrophenol and sodium azide made the synthesis of ‐galactosidase more responsive to exogenous cyclic AMP because the effect of cyclic AMP with dinitrophenol or with sodium azide was markedly greater than the sum of the separate effects of cyclic AMP and of each of the uncouplers. This effect of the uncouplers was unrelated to their action on oxidative phosphorylation because it still occurred under anaerobic conditions. It was also not due to increased accumulation of cyclic AMP by enhanced uptake or by inhibition of cyclic AMP‐phosphodiesterase.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-71-2-311
1972-07-01
2021-08-04
Loading full text...

Full text loading...

/deliver/fulltext/micro/71/2/mic-71-2-311.html?itemId=/content/journal/micro/10.1099/00221287-71-2-311&mimeType=html&fmt=ahah

References

  1. ABOUD M., BURGER M. 1970; The effect of catabolite repression and of cyclic 3´,5´ adenosine mono‐phosphate on the translation of the lactose messenger RNA in Escherichia coli.. Biochemical and Biophysical Research Communications 38:1023–1031
    [Google Scholar]
  2. ABOUD M., BURGER M. 1971a; Cyclic 3´,5´ adenosine monophosphate‐phosphodiesterase and the release of catabolite repression of β‐galactosidase by exogenous cyclic 3´,5´ adenosine monophosphate in Escherichia coli. Biochemical and Biophysical Research Communications 43:174–182
    [Google Scholar]
  3. ABOUD M., BURGER M. 1971b; Adenosine triphosphate and catabolite repression of β‐galactosidase in Escherichia coli.. Biochemical and Biophysical Research Communications 45:190–197
    [Google Scholar]
  4. CALCOTT P., POSTGATE J. R. 1971; Substrate‐accelerated death: Role of recovery medium and prevention by 3´,5´ cyclic AMP. Journal of General Microbiology 66:i
    [Google Scholar]
  5. CHAMBERS D. A., ZUBAY G. 1969; The stimulatory effect of cyclic adenosine 3´,5´ monophosphate on DNA directed synthesis of β‐galactosidase in a cell‐free system.. Proceedings of the National Academy of Sciences of the United States of America 68:118–122
    [Google Scholar]
  6. CHEFURKA W., YAPO A., NISMAN B. 1970; In vitro synthesis of β‐galactosidase by membrane fractions of E. coli.. Canadian Journal of Biochemistry 244:5828–5835
    [Google Scholar]
  7. DE CROMBRUGGHE B., PERLMAN R. L., YARMUS H. E., PASTAN I. 1969; Regulation of inductible enzyme synthesis in Escherichia coli by cyclic adenosine 3´,5´‐monophosphate.. Journal of Biological Chemistry 244:5828–5835
    [Google Scholar]
  8. DOBROGOSZ W. J. 1965; The influence of nitrate and nitrite reduction on catabolite repression in Escherichia coli.. Biochimica et biophysica acta 100:553–566
    [Google Scholar]
  9. DOBROGOSZ W. J. 1966; Altered end-product pattern and catabolite repression in Escherichia coli.. Journal of Bacteriology 91:2263–2269
    [Google Scholar]
  10. GALEOTTI T., KOVAC L., HESS B. 1968 Interference of uncoup. Nature London: 218194–196
    [Google Scholar]
  11. JACQUET M., KEPES A. 1969; The step sensitive to catabolite repression and its reversal by 3´,5´ cyclic AMP during induced synthesis of β‐galactosidase in E. coli.. Biochemical and Biophysical Research Communications 36:84–92
    [Google Scholar]
  12. MAGASANIK B. 1961; Catabolite repression.. Cold Spring Harbor Symposia of Quantitative Biology 26:249–256
    [Google Scholar]
  13. MAKMAN R. S., SUTHERLAND E. W. 1965; Adenosine 3´,5´phosphate in Escherichia coli.. Journal of Biological Chemistry 240:1309–1313
    [Google Scholar]
  14. MANDELSTAM J. 1961; Induction and repression of β‐galactosidase in non-growing Escherichia coli.. Biochemical Journal 79:489–493
    [Google Scholar]
  15. OKINAKA R. T., DOBROGOSZ W. J. 1967; Catabolite repression and Pasteur effect inEscherichia coli. . Archives of Biochemistry and Biophysics 120:451–453
    [Google Scholar]
  16. PASTAN I., PERLMAN R. L. 1969; Repression of β‐galactosidase by glucose in phosphotransferase mutants of Escherichia coli. Repression in the absence of glucose phosphorylation.. Journal of Biological Chemistry 244:5836–5842
    [Google Scholar]
  17. PaVLASOVA E., HAROLD F. M. 1969; Energy coupling in transport of β‐galactosides by Escherichia coli: Effect of proton conductors.. Journal of Bacteriology 98:198–204
    [Google Scholar]
  18. PERLMAN R. L., PASTAN I. 1968; Cyclic 3´,5´AMP: Stimulation of β‐galactosidase and tryptophanase induction in E. coli.. Biochemical and Biophysical Research Communications 30:656–664
    [Google Scholar]
  19. POSTGATE J. R., HUNTER J. R. 1963 Acceleration of bacterial death by growth substrate.. Nature London: 198273
    [Google Scholar]
  20. POSTGATE J. R., HUNTER J. R. 1964; Accelerated death of Aerobacter aerogenes starved in the presence of growth‐limiting substrates.. Journal of General Microbiology 34:459–473
    [Google Scholar]
  21. STRANGE R. E., DARK F. A. 1965; Substrate‐accelerated death of Aerobacter aerogenes.. Journal of General Microbiology 39:215–228
    [Google Scholar]
  22. STRANGE R. E., HUNTER J. R. 1966; Substrate-accelerated death of nitrogen-limited bacteria.. Journal of General Microbiology 44:255–262
    [Google Scholar]
  23. TYLER B., MAGASANIK B. 1970; Physiological basis of transient repression of catabolite enzymes in. Escherichia coli. Journal of Bacteriology 102:411–422
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-71-2-311
Loading
/content/journal/micro/10.1099/00221287-71-2-311
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error