1887

Abstract

SUMMARY: A long-chain fatty-acid fraction obtained from the marine alga, , as well as decanoic, dodecanoic and hexadecanoic acids at levels of 250 g/ml induced lysis of various Trypanosomatidae. However, octanoic and -9-octa-decenoic acids at higher concentrations had no effect. Decanoic, dodecanoic and hexadecanoic acids at levels below 100 g/ml inhibited motility of the promasti-gotes of and , and the epimastigotes and trypo-mastigotes of was relatively resistant to fatty acids and was not affected by decanoic acid at this level.

The lysis induced by the marine algal fatty acids and by decanoic and dodecanoic acids was preceded by the formation of rounded forms ofthehaemoflagellates which indicated the loss of membrane structure.

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/content/journal/micro/10.1099/00221287-70-3-491
1972-05-01
2022-01-21
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