1887

Abstract

Summary: Various features of the growth curve of a synchronous culture of bacteria are related to the generation time distribution of the cells, and the parent-progeny generation time correlation coefficients. It is suggested that the examination of synchronous growth enables the parameters of the generation time distribution, and the correlation coefficients, to be extracted relatively simply and their dependence upon environment to be investigated. Methods of estimating the degree of synchronization, and some corrections for the effects of imperfect synchronization, are suggested.

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/content/journal/micro/10.1099/00221287-70-1-99
1972-04-01
2021-10-28
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References

  1. Cramer H. 1946 Mathematical Methods of Statistics Princeton, New Jersey: University Press;
    [Google Scholar]
  2. Goodwin B. C. 1970; Model of the bacterial growth cycle. Journal of Theoretical Biology 28:375
    [Google Scholar]
  3. Harris T. E. 1963 The Theory of Branching Processes Berlin: Springer Verlag;
    [Google Scholar]
  4. Harvey J. D. 1972; Parameters of the generation time distribution of Escherichia coli B/r. Journal of General Microbiology 70:109–114
    [Google Scholar]
  5. Helmstetter C. E., Cummings D. J. 1964; An improved method for the selection of bacterial cells at division. Biochemica et biophysica acta 82:608–610
    [Google Scholar]
  6. Kendal D. G. 1952; On the choice of a mathematical model to represent normal bacterial growth. Journal of the Royal Statistical Society 14:41–44
    [Google Scholar]
  7. Koch A. L., Schaechter M. 1962; A model for the statistics of the cell division process. Journal of General Microbiology 29:435–454
    [Google Scholar]
  8. Kubitschek H. E. 1962a; Normal distribution of cell generation rate. Experimental Cellular Research 26:439–450
    [Google Scholar]
  9. Kubitschek H. E. 1962b; Discrete distributions of generation rate. Nature; London: 195350–351
    [Google Scholar]
  10. Kubitschek H. E. 1966a; Normal distribution of cell generation rate. Nature; London:
    [Google Scholar]
  11. Kubitschek H. E. 1966b; Generation times : ancestral dependence and dependence upon cell size. Experi-mental Cellular Research 43:30–38
    [Google Scholar]
  12. Powell E. O. 1956; Growth rate and generation time of bacteria with special reference to continuous culture. Journal of General Microbiology 15:492–511
    [Google Scholar]
  13. Powell E. O. 1964; A note on Koch and Schaechter's hypothesis about growth and fission of bacteria. Journal of General Microbiology 37:231–249
    [Google Scholar]
  14. Powell E. O. 1969; Generation times of bacteria: real and artificial distributions. Journal of General Microbiology 58:141–144
    [Google Scholar]
  15. Rahn O. 1932; A chemical explanation of the variability of the growth rate. Journal of General Physiology 15:257–277
    [Google Scholar]
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