SUMMARY: Pleuropneumonia-like organisms (PPLO) of human origin are very susceptible to the deleterious action of soaps. There was no significant difference in the antibacterial action of soaps containing 2% hexachlorophene and an ordinary-hand soap, on the pleuropneumonia-like organisms tested. The great susceptibility of these organisms to soap probably masks any action which the hexachlorophene contained in the medicated soaps might have on PPLO. The deleterious action of soaps on pleuropneumonia-like organisms is bactericidal.
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