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Volume 7, Issue 3-4

A Phase-contrast Study of Reproduction in Mycelial Strains of Avian Tubercle Bacilli Free

Abstract

SUMMARY: The reproductive processes occurring in mycobacteria were studied in mycelial strains of avian tubercle bacilli and the developments recorded by phase-contrast microscopy. Three main developments were traced: (1) Disintegrating mycelial branches release micro-rods (as small as 0·2 .), which later elongate into bacillary forms. (2) Parts of some mycelia produce filamentous sprouts which grow into entangled nests of filaments, and finally give rise to spherical colonics of short rods. (3) Some mycelial branches become swollen and very dense. Later they become more transparent and parallel rows of filaments are revealed lying orientated along the length of the branches. The typical morphology of orientated and non-orientated growth is explained with reference to the modes of development. Growth is preceded by a stage of mycelial proliferation, which is mainly non-acid-fast, but results in microeolonies of the normal acid-fast rod. The relation between some atypical structures and L-forms is discussed.

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© Society for General Microbiology, 1952
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1952-11-01
2024-10-13
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References

  1. Alexander-Jackson E. 1945; A hitherto undemonstrated Zoogleal form of Mycobacterium tuberculosis. Ann. N.Y. Acad. Sci 46:127
     [Google Scholar]
  2. Bloch H. 1950; Enzymatic characteristics of suspensions of different mycobacteria. Amer. Rev. Tuberc 61:270
     [Google Scholar]
  3. Brieger E. M. 1945; Observations on the species pathogenicity of the tubercle bacillus in intra-amniotic infection. J.Path. Bact 57:282
     [Google Scholar]
  4. Brieger E. M., Fell H. B. 1945; Warm-stage observations on the initial development of the avian tubercle bacillus cultivated in embryo extract. J. Hyg., Camb 44:158
     [Google Scholar]
  5. Brieger E. M., Fell H. B. 1946; Warm-stage observations on the development of pseudo-mycelia in cultures of avian tubercle bacilli grown in dilute embryo extract. J. Hyg., Camb 44:256
     [Google Scholar]
  6. Brieger E. M., Robinow C. F. 1947; Demonstration of chromatinic structures in avian tubercle bacilli in the early stages of development. J. Hyg., Camb 45:413
     [Google Scholar]
  7. Kahn M. C. 1932; Weitere Bemerkungen zur morphologischen Untersuchung über den Entwicklungszyklus der Einzelzelle des Tuberkelbazillus. Zbl. Bakt 1. Abt. Orig 125:451
     [Google Scholar]
  8. Klieneberger-Nobel E. 1951; Filterable forms of bacteria. Bact. Rev 15:77
     [Google Scholar]
  9. Maffucci A. 1892; Die Hühnertuberkulose. Z. Hyg. InfektKr 11:445
     [Google Scholar]
  10. Middlebrook G. 1950; Recent advances in bacteriological research in tuberculosis. Recent Adv. Tuberc. Res 3:132
     [Google Scholar]
  11. Nedelkovitch J. 1950; Mode de multiplication du bacilli de Koch. Morphologie du bacilli et de ses colonies. Quelques sources d’erreurs. Ann. Inst. Pasteur 78:177
     [Google Scholar]
  12. Ørskov J. 1923 Investigations into the Morphology of the Ray Fungi Copenhagen: Levin and Munksgaard;
     [Google Scholar]
  13. Porter K. R., Yegian D. 1945; Some artifacts encountered in stained preparations of tubercle bacilli. II. Much granules and beads. J. Bact 50:263
     [Google Scholar]
  14. Strangeways T. S. P. 1924 The Technique of Tissue Culture ‘in vitro’ Cambridge: Heffer and Sons Ltd;
     [Google Scholar]
  15. Sweaney H. 1928; The granules of the tubercle bacillus. Amer. Rev. Tuberc 17:53
     [Google Scholar]
  16. Wyckoff R. W. G. 1934; A micro-motion picture study of the growth of tubercle bacilli from cold-blooded animals. Amer. Rev. Tuberc 24:389
     [Google Scholar]
/content/journal/micro/10.1099/00221287-7-3-4-287
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A Phase-contrast Study of Reproduction in Mycelial Strains of Avian Tubercle Bacilli
Microbiology 7, 287 (1952); https://doi.org/10.1099/00221287-7-3-4-287
/content/journal/micro/10.1099/00221287-7-3-4-287
/content/journal/micro/10.1099/00221287-7-3-4-287
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