SUMMARY: The adaptation of a genetically deficient strain of to the utilization of lactose was shown to involve overgrowth of the population by a small number of mutants. The rate of mutation to lactose utilization is about 2 x 10 per bacterium per generation. This rate is not influenced by lactose or a series of substances related to that sugar. The distribution of these mutants among different cultures is in agreement with that expected on the basis of random mutation. These results are discussed in connexion with the theories of Hinshelwood on bacterial adaptation, and in relation to the problem of specifically induced mutation.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error