1887

Abstract

Summary: When is grown in a simple defined medium with limiting concentrations of nicotinic acid but all other constituents in excess, growth as measured by dry-weight determinations continues for several hours after the disappearance of all detectable nicotinic acid from the medium. A linear phase of protoplasmic synthesis and of oxygen uptake follows this disappearance and lasts for 2·5–3 hr., while the amount of recoverable nicotinic acid in the cells remains constant. It is suggested that, during the period of linear growth, the rate of protoplasmic synthesis is determined by the presence within the total cell population of a more or less constant amount of nicotinic acid or its active derivatives.

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/content/journal/micro/10.1099/00221287-7-1-2-107
1952-08-01
2022-01-20
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References

  1. Barton-Wright E.C. 1946 Practical Methods for the Microbiological Assay of the Vitamin B Complex and Essential Amino-acids. London:: Ashe Laboratories, Ltd.;
    [Google Scholar]
  2. Fildes P. 1938; The growth of Proteus on ammonium lactate plus nicotinic acid. Brit. J. exp. Path. 19239
    [Google Scholar]
  3. Henrici A.T. 1928 Morphologic Variation and the Rate of Growth of Bacteria. Springfield,111:: Charles C. Thomas.;
    [Google Scholar]
  4. Mcilwain H. 1940; Pyridine-3-sulphonic acid and its amide as inhibitors of bacterial growth. Brit. J. exp. Path. 21136
    [Google Scholar]
  5. McIlwain H., Hughes D.E. 1948; Decomposition and synthesis of cozymase by bacteria. Biochem. J. 43:60
    [Google Scholar]
  6. Miles A.A., Misha S.S. 1938; The estimation of the bactericidal power of the blood. J. Hyg., Camb. 38:732
    [Google Scholar]
  7. Miller L., Houghton J.A. 1945; The micro-kjeldahl determination of the nitrogen content of amino-acids and proteins. J. biol. Chem. 159:373
    [Google Scholar]
  8. Monod J. 1949; The growth of bacterial cultures. Ann. Rev. Microbiol. 3:371
    [Google Scholar]
  9. Morel M. 1941; L’usure de la nicotinamide chez Proteus vulgaris. Ann. Inst.Pasteur 67:285
    [Google Scholar]
  10. Saunders F., Dorfman A., Koser S.A. 1941; The role of nicotinamide and related compounds in the metabolism of certain bacteria. J. biol. Chem. 138:69
    [Google Scholar]
  11. Schaeffer P. 1950; Croissance et respiration d’une souche streptomycino-exigeante de Bacillus cereus privée de l’antibiotique-facteur de croissance. Ann. Inst.Pasteur 78:624
    [Google Scholar]
  12. Sykes J.A., Reed R. 1949; The control of the swarming of Proteus vulgaris by boric acid. J. gen. Microbiol. 3:117
    [Google Scholar]
  13. Wilson G.S. 1922; The proportion of viable bacteria in young cultures with especial reference to the technique employed in counting. J. Bact. 7:405
    [Google Scholar]
  14. Wright H.D. 1933; The importance of adequate reduction of peptone in the preparation of media for the pneumococcus and other organisms. J. Path. Bact. 37:257
    [Google Scholar]
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