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SUMMARY: Methods are described for isolating the walls of the intracellular parasite Mycobacterium lepraemurium in good yields. The walls were treated with solvents and reagents and their effects were followed by chemical analyses and electron microscopy. The walls resemble those of other mycobacteria, consisting of muco-peptide, arabinogalactan and ester-linked lipid. The lipid forms the outer, electron-transparent layer of the wall. The information available so far offers no explanation of the bacterium’s outstanding resistance to destruction by phagocytic cells.
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