SUMMARY: Vegetative development of may follow either one of two patterns of morphogenesis (hyphal-yeastlike dimorphism) depending upon the presence or absence of manganese ions in the culture medium. The addition of exogenous amino acids, vitamins and other trace metals had no significant effect upon morphogenetic development or aflatoxin B synthesis. The yeastlike forms are capable of continuous aflatoxin B synthesis under non-proliferating conditions. Varying the Mn concentration from 7.3 x 10 to 7.3 x 10 mM causes a morphological change from yeastlike to hyphal development in a synthetic medium. The yeastlike forms are stable and resist osmotic shock.


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