
Full text loading...
SUMMARY
Mutants of Neurospora crassa, Escherichia coli and Salmonella typhimurium are described which are inhibited by CO2 at concentrations which do not inhibit the parental strains from which the mutants were derived. Sensitivity to inhibition by CO2 is caused by single gene mutations. The CO2 inhibitions are reversed by specific substances; for example, the CO2 inhibition of a methionine-requiring mutant of N. crassa is reversed by purines, and the CO2inhibition of a prototroph of E. coli is reversed by methionine or vitamin B12.
The nature of the defects in the CO2-inhibited mutants is discussed.
Article metrics loading...
Full text loading...
References