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Summary: We have isolated auxotrophic mutants of Streptomyces coelicolorwhich can grow on a minimal medium without growth factors when the gas phase is supplemented with CO2. Usually they have an alternative requirement for a specific growth factor such as arginine, purines or vitamins. Some of the CO2 mutants resemble those already known in Neurosporacrassa and Escherichia coli but others present novel phenotypes.
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