The Effect of Temperature on the Free

Abstract

SUMMARY : A strain of known to produce penicillinase adaptively was tested for penicillin sensitivity at different temperatures. With small inocula, the organisms grew freely at 37° in concentrations of penicillin up to a hundred times greater than those which completely suppressed their growth at 42°. This difference in apparent sensitivity almost disappeared when the inoculum was very heavy or consisted of cells which had been allowed to adapt by previous growth in the presence of penicillin.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-6-3-4-369
1952-05-12
2024-03-29
Loading full text...

Full text loading...

/deliver/fulltext/micro/6/3-4/mic-6-3-4-369.html?itemId=/content/journal/micro/10.1099/00221287-6-3-4-369&mimeType=html&fmt=ahah

References

  1. Knox R. 1945; The effect of tetrathionate on bacterial growth. Brit. J. exp. Path. 26:146
    [Google Scholar]
  2. Knox R. 1950; Tetrathionase: The differential effect of temperature on growth and adaptation. J. gen. Microbiol. 4:388
    [Google Scholar]
  3. Knox R., Pollock M.R. 1944; . Bacterial tetrathionase: adaptation without demonstrable cell growth. Biochem. J 38:299
    [Google Scholar]
  4. Luria S.E. 1946; A test for penicillin sensitivity and resistance in staphylococcus. Proc. Soc. exp. Biol., N.Y. 61:46
    [Google Scholar]
  5. Marks J. 1951; Effects of hyperthermia and antibacterial agents on tubercle bacilli. Brit. med. J. ii:1318
    [Google Scholar]
  6. Pasteur L., Joubert J., Chamberland C. 1878; La theorie des germes et ses applications à la médecine et a la chirurgie. Bull. Acad. Méd., Paris 2nd ser. 7:432
    [Google Scholar]
  7. Pollock M.R. 1945; The influence of temperature on the adaptation of ’tetrathionase ’ in washed suspensions of Bact. paratyphosum B. Brit. . J. exp. Path. 26:410
    [Google Scholar]
  8. Pollock M.R. 1950; Penicillinase adaptation in B. cereus: Adaptive enzyme formation in the absence of free substrate. Brit. J. exp. Path. 31:739
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-6-3-4-369
Loading
/content/journal/micro/10.1099/00221287-6-3-4-369
Loading

Data & Media loading...

Most cited Most Cited RSS feed