Summary: Certain races of streptococcal phage with a normal lytic action on some strains of streptococci were found to be adsorbed on, and to inhibit the growth of, other strains, without the occurrence of lysis or multiplication of the phage. One race of phage inhibited the growth of several streptococcal strains which had hitherto been considered unrelated to one another on the basis of their reactions to lytic phages. Cultures which recovered from temporary inhibition by phage contained variants which were resistant both to inhibition and to lysis by phages which attacked the original strain. This resistance is, however, short-lived as compared with the resistance of variants obtained through the action of a lytic phage.


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