Growth and Toxin Synthesis in Batch and Chemostat Cultures of Corynebacterium Diphtheriae

References

1. Alouf J. E. 1958 Etude physiologique et biochimique de la toxinogenise diphterique. Ph.D. thesis University of Paris, Faculty of Pharmacy; Series E. No. 60
   [Google Scholar]
2. Barksdale W. L., Garmise L., Rivera R. 1961; Toxinogeny in Corynebacterium diphtheriae . J. Bact 81:527
   [Google Scholar]
3. Edwards D. C., Seamer P. A. 1960; The uptake of iron by Corynebacterium diphtheriae growing in submerged culture. J. gen. Microbiol 22:705
   [Google Scholar]
4. Van Hemert P. A. 1964; The Bilthoven Unit for submerged cultivation of micro-organisms. Biotech. Bioeng 6:381
   [Google Scholar]
5. Van Hemert P. A., Van Wezel A. L. 1966The course of pH in diphtheria toxin producti on Symp. Series immunobiol. Standard 3221 Basel & New York: Karger;
   [Google Scholar]
6. Van Hemert P. A., Kilburn D. G., Righelato R. C., Van Wezel A. L. 1969; A steam sterilis- able electrode of the galvanic type for the measurement of dissolved oxygen. Biotech. Bioeng. (in Press)
   [Google Scholar]
7. Hirai T., Uchida T., Shinmen Y., Yoneda M. 1966; Toxin production by Corynebacterium diphtheriae under growth-limiting conditions. Biken J 9:19
   [Google Scholar]
8. Linggood F. V., Fenton E. L. 1947; The production of diphtheria toxin by submerged culture in shaking flasks. Br. J. exp. Path 28:354
   [Google Scholar]
9. Monod J. 1950; La technique de culture continue. Théorie et applications. Annls Inst. Pasteur, Paris 79:390
   [Google Scholar]
10. Novick A., Szilard L. 1950; Description of the chemostat. Science, N. Y 112:715
    [Google Scholar]
11. Pappenheimer A. M., Jun J. 1955; The pathogenicity of diphtheria. Symp. Soc. gen. Microbiol 5:40
    [Google Scholar]
12. Pappenheimer A. M., Jun J., Hendee E. D. 1947; Diphtheria toxin. IV. The iron enzymes of Corynebacterium diphtheriae and their possible relation to diphtheria toxin. J. biol. Chem 167:701
    [Google Scholar]
13. Pappenheimer A. M., Jun J., Miller P. A., Yoneda M. 1962; Kinetics of diphtheria toxin formation. J. gen. Microbiol 28:531
    [Google Scholar]
14. Park W. H., Williams A. W. 1896; The production of diphtheria toxin. J. exp. Med 1:164
    [Google Scholar]
15. Pirt S. J., Thackeray E. J., Harris-Smith J. 1961; The influence of environment on antigen production by Pasteurella pestis studied by means of the continuous flow technique. J. gen. Microbiol 25:119
    [Google Scholar]
16. Raynaud M. 1966; Relation between growth and toxin synthesis. Symp. Series immunobiol. Standard 3183 Basel & New York: Karger;
    [Google Scholar]
17. Raynaud M., Turpin A., Mangalo R., Bizztni B., Pery R. 1954; Growth and toxinogenesis. Annls Inst. Pasteur, Paris 87:599
    [Google Scholar]
18. Righelato R. C. 1969; The distribution of iron in iron-deficient toxin-synthesising and in excess-iron non-toxin-synthesising Corynebacterium diphtheriae . J. gen. Microbiol 58:411
    [Google Scholar]
19. Righelato R. C., Van Hemert P. 1969; Toxinogenesis in continuous cultures of Corynebacterium diphtheriae . Proceedings of 4th International Symposium on Continuous Culture of Micro organisms. Prague: Academia
    [Google Scholar]
20. Stickland L. H. 1951; The determination of small quantities of bacteria by means of the biuret reaction. J. gen. Microbiol 5:698
    [Google Scholar]
21. Tasman A., Brandwijk A. C. 1940; Experiments on metabolism with Corynebacterium diphtheriae III. J. infect. Dis 67:282
    [Google Scholar]
22. Zaccharias B., Björklund M. 1968; Continuous production of Clostridium tetani toxin. Appl. Microbiol 16:69
    [Google Scholar]