1887

Abstract

SUMMARY: Carbenicillin, a 9-alpha carboxybenzyl penicillin, is bactericidal only for strains which are resistant to less than 125 μg./ml. of ampicillin. All and strains in which penicillinase is a surface enzyme are resistant to Carbenicillin. and strains in which production of beta-lactamase is episomally mediated are resistant to both ampicillin and Carbenicillin. A non-hydrolyzable penicillin (methicillin or dicloxacillin) does not allow Carbenicillin to exert its anti-bacterial effect against resistant strains of or Carbenicillin shows no synergy with penicillinase-resistant penicillins.

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/content/journal/micro/10.1099/00221287-58-3-301
1969-11-01
2019-10-22
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