SUMMARY: A single dose of γ-radiation to b gave a semi-logarithmic dose-response curve. A second irradiation 3, 6, or 18 hr after a priming dose of 8 krad showed that the cells had become more radio-sensitive during the incubation between irradiations.

When mercaptoethylamine was present during irradiation, protection against the lethal effects of the γ-radiation occurred. After a priming dose to the bacteria in the presence of the radio-protective chemical, and incubations for 3,6, or 18 hr in its absence, a second irradiation in the absence of the chemical showed them to be much more radio-resistant than the normal unprotected b. This indicates that the presence of the protector during irradiation alters the type of damage induced or the development and repair of that damage.


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