1887

Abstract

SUMMARY

The properties of a temperature-sensitive mutant of in which DNA synthesis is specifically and reversibly inhibited above 40° are described. When incubated at 45° there was no detectable breakdown of DNA in the mutant and the synthesis of deoxynucleoside triphosphates was normal. The temperature-sensitive element affects DNA synthesis but not and (unlike an initiator) it appears to be needed for DNA synthesis throughout the replication cycle.

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/content/journal/micro/10.1099/00221287-56-1-87
1969-04-01
2022-01-18
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