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SUMMARY: The incorporation and metabolism of glucose by the blue-green alga Anabaena variabilis is described. Experiments with [14C]glucose indicated that this compound contributed up to 46 % of the total dry wt of organism. Respiratory studies with [I-14C] and [6-14C] showed that the pentose phosphate pathway was the major route of glucose dissimilation. No evidence of alteration in enzyme concentration after growth in the presence of glucose was found in the ten examples of glycolytic and pentose phosphate pathway enzymes examined. Enzymes from both pathways were affected by the end-products. These results are discussed in relation to autotrophic metabolism in blue-green algae.
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