SUMMARY: Two partially characterized groups of compounds were isolated from an apple variety (Miller's Seedling) which has polygenic resistance to apple scab. These compounds inhibited germination of conidia of and interfered with pigment production in log-phase cultures of the organism. They were more abundant in varieties of apple resistant to scab than in susceptible varieties, and increased in the leaves of resistant varieties after inoculation with conidia. When applied to the foliage of a variety of apple normally susceptible to scab these compounds conferred a measure of protection against the disease. The subject of physiological resistance of plants to microbial attack is discussed.


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