SUMMARY: This report shows that some auxotrophic mutants of can grow on a minimal medium without growth factors when the gas phase is supplemented with carbon dioxide. Mutants which respond to CO are called CO mutants. The CO mutants of resemble those already known in Neurospora. When the gas phase is not supplemented with CO most of the mutants respond to other specific growth factors such as arginine, uracil, adenine, succinate or isoleucine+valine, depending upon the locus of their mutation. One mutant is an obligate CO mutant. The CO effects shown by these mutants are discussed in relation to the general problem of CO effects in micro-organisms.


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