1887

Abstract

SUMMARY

Hypocholesteremic compounds, triparanol, SKF 525-A, SKF 3301-A, SKF 16467-A, inhibited the multiplication of some bacteria and ascomycetes; phycomycetes were not inhibited. Gram-positive bacteria were most sensitive to these compounds. Dimethyl or diethyl aminoethanol and SKF 2314, compounds resembling the major moieties of the SKF compounds, were not inhibitory alone or together; the whole molecule was necessary for inhibition. Inhibition by triparanol of the multiplication of several Gram-positive bacteria was annulled by albumin and ergosterol; oleic acid and squalene were mostly inactive.

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/content/journal/micro/10.1099/00221287-50-2-271
1968-02-01
2022-05-21
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