SUMMARY: Hypocholesteremic compounds, triparanol, SKF 525-A, SKF 3301-A, SKF 16467-A, inhibited the multiplication of some bacteria and ascomycetes; phycomycetes were not inhibited. Gram-positive bacteria were most sensitive to these compounds. Dimethyl or diethyl aminoethanol and SKF 2314, compounds resembling the major moieties of the SKF compounds, were not inhibitory alone or together; the whole molecule was necessary for inhibition. Inhibition by triparanol of the multiplication of several Gram-positive bacteria was annulled by albumin and ergosterol; oleic acid and squalene were mostly inactive.


Article metrics loading...

Loading full text...

Full text loading...


Most cited this month Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error