SUMMARY: A study has been made of the uptake of inositol from liquid media by and 4228. All the available inositol was rapidly removed from the medium so long as growth continued. Small amounts were recovered from the organisms by water extraction, and up to 75% from the yeast by acid hydrolysis. This bound inositol in the yeast possessed properties resembling those of phytin. On media deficient in inositol, cell division was incomplete. No influence of inositol on the respiratory system of could be detected. γ-Hexachlorohexane inhibited growth and respiration of intact yeast cells, but not respiration of dried yeast preparations; its effect was not reversed by inositol. Streptidine, strepturea and streptamine neither inhibited growth nor could replace inositol as a growth factor.


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