1887

Abstract

The heat-stability of the T antigen of strains of grown in Pope &Smith (1932) broth (containing maltose and yeast) with added pancreatic extract varied considerably from strain to strain; with several strains 30 minutes' boiling was insufficient to eliminate all T agglutinability.

By heating suspensions of streptococci to 80 for 30 min. and then treating the heated suspensions with trypsin-containing pancreatic extract for a few hours, T antigen was obtained in solution and could be demonstrated by precipitin tests with appropriate type-specific sera.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-5-4-640
1951-12-01
2021-08-05
Loading full text...

Full text loading...

/deliver/fulltext/micro/5/4/mic-5-4-640.html?itemId=/content/journal/micro/10.1099/00221287-5-4-640&mimeType=html&fmt=ahah

References

  1. Elliott S. D. 1943; Type relationships amongst Group A streptococci. Brit. J. exp. Path 24:159
    [Google Scholar]
  2. Lancefield Rebecca C. 1940-1; Specific relationship of cell composition to biological activity of the haemolytic streptococci. Harvey Lect 36:251
    [Google Scholar]
  3. Lancefield Rebecca C., Dole V. P. 1946; The properties of T antigens extracted from Group A streptococci. J. exp. Med 84:449
    [Google Scholar]
  4. Pope C. G., Smith Margaret L. 1932; The routine preparation of diphtheria toxin of high value. J. Path. Bact 35:573
    [Google Scholar]
  5. Stewart W. A., Lancefield Rebecca C., Wilson A. T., Swift H. F. 1944; Studies on the antigenic composition of Group A haemolytic streptococci. IV. Related T but distinct M antigens in Types 15,17, 19, 23, 30 and in Types 4, 24, 26, 28, 29, 46. Identification by slide agglutination. J. exp. Med 79:99
    [Google Scholar]
  6. Swift H. F., Wilson A. T., Lancefield Rebecca C. 1943; Typing Group A haemolytic streptococci by M precipitin reactions in capillary pipettes. J. exp. Med 78:127
    [Google Scholar]
  7. Todd E. W., Hewitt L. F. 1932; A new culture medium for the production of antigenic streptococcal haemolysin. J. Path. Bact 35:973
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-5-4-640
Loading
/content/journal/micro/10.1099/00221287-5-4-640
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error