1887

Abstract

SUMMARY: A modification of the Hirst & Pickels photoelectric densitometer and its application to work on influenza virus haemagglutination are described. The methods used are believed to reduce to a minimum the inherent margin of error of virus and serum antibody assays based upon the haemagglutination reaction. In order to make full use of data thus obtained precise assessment of the significance of differences of titre is essential, and for this purpose two simple statistical tests have been applied and their application illustrated by an example.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-5-3-546
1951-08-01
2021-08-02
Loading full text...

Full text loading...

/deliver/fulltext/micro/5/3/mic-5-3-546.html?itemId=/content/journal/micro/10.1099/00221287-5-3-546&mimeType=html&fmt=ahah

References

  1. Hirst G. K., Pickels E. G. 1942; A method for the titration of influenza haemagglutinin and influenza antibodies with the aid of a photoelectric densitometer. J. Immunol 45:273
    [Google Scholar]
  2. Needham N. V. 1947; A photometric method for the comparative evaluation of disinfectants. J. Hyg., Camb 45:1
    [Google Scholar]
  3. Salk J. 1944; A simplified procedure for titrating haemagglutinating capacity of influenza-virus and the corresponding antibody. J. Immunol 49:87
    [Google Scholar]
  4. Smith W., Westwood M. A. 1949; Factors involved in influenza haemagglutination reactions. Brit. J. exp. Path 30:48
    [Google Scholar]
  5. Wolff H. I. 1949; The use of the haemagglutination inhibition test in epidemiological influenza-virus studies. J. Hyg., Camb 47:396
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-5-3-546
Loading
/content/journal/micro/10.1099/00221287-5-3-546
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error