@article{mbs:/content/journal/micro/10.1099/00221287-49-3-411, author = "Leavitt, R. I.", title = "Microbial Oxidation of Hydrocarbons. Oxidation of p-Isopropyltoluene by a Pseudomonas sp.", journal= "Microbiology", year = "1967", volume = "49", number = "3", pages = "411-420", doi = "https://doi.org/10.1099/00221287-49-3-411", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-49-3-411", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "SUMMARY Whole organisms and soluble extracts of a Pseudomonas sp. were examined for their ability to oxidize suspected intermediates in the oxidation of p-isopropyltoluene. A comparison of the relative activities of glucose-grown and p-isopropyltoluene-grown bacteria and their extracts indicated that p-isopropylbenzyl alcohol, p-isopropylbenzaldehyde and p-isopropyl-benzoic acid are intermediates in the oxidation of the hydrocarbon, p-isopropylbenzoic acid was formed during growth on p-isopropyltoluene and this was also shown to be a product of the oxidation of p-isopropyltoluene, p-isopropylbenzyl alcohol and p-isopropylbenzaldehyde by soluble extracts prepared from p-isopropyltoluene-grown bacteria. The enzymes which catalyze the oxidation of p-isopropyltoluene were repressed by glucose and induced by growth on either p-isopropyltoluene or p-isopropylbenzoic acid.", }