1887

Abstract

SUMMARY

Production of pili directed either by the sex factor F or by the drug-resistance factor R 100 in 12 is regulated by a gene which acts by producing a repressor, and the mutant R 100–1 no longer produces this repressor. The specific pilus determined by R 100–1 resembled the F pilus morphologically, but differed in its affinity for F-specific RNA phages. Mutants of F and R 100–1 which had lost the ability to synthesize pili could each restore to the other the ability to produce pili on mixed infection of the same host.

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/content/journal/micro/10.1099/00221287-49-1-89
1967-10-01
2024-12-02
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References

  1. Akiba T., Koyama T., Isshiki T., Kimura S., Fukushima T. 1960; Studies on the mechanism of development of multiple drug resistant Shigella strains. Jap. J. med. Sci. Biol186646
    [Google Scholar]
  2. Brenner S., Horne R. W. 1959; A negative staining method for high resolution electron microscopy of viruses. Biochim. biophys. Acta 34:103
    [Google Scholar]
  3. Brinton C. C. 1965; The structure, function, synthesis and genetic control of bacterial pili and a molecular model for DNA and RNA transport in gram-negative bacteria. Trans. N. Y. Acad. Sci. 27:1003
    [Google Scholar]
  4. Brinton C. C., Gemski P., Carnahan J. 1964; A new type of bacterial pilus genetically controlled by the fertility factor of E coli k-12 and its role in chromosome transfer. Proc. natn. Acad. SciU.S.A 52776
    [Google Scholar]
  5. Brinton C. C., Gemski P., Falkow S., Baron L. S. 1961; Location of the piliation factor on the chromosome of Escherichia coli . Biochem. biophys Res. Commuti. 5:293
    [Google Scholar]
  6. Cavalli-Sforza L. L. 1950; La sessualita nei batten. Boll. 1st. sieroter. milan. 29:281
    [Google Scholar]
  7. Crawford E. M., Gesteland R. F. 1964; The adsorption of bacteriophage R-17. Virology 22:165
    [Google Scholar]
  8. Cuzin F. 1962; Mutants défeetifs de l’episome sexuel chez Escherichia coli k-12. C. r. hebd. Séanc. Acad. Sci., Paris 255:1149
    [Google Scholar]
  9. Datta N., Lawn A. M., Meynell E. 1966; The relationship of F type piliation and F phage sensitivity to drug resistance transfer in R+F Escherichia coli k 12. J. gen. Microbiol. 45:365
    [Google Scholar]
  10. Davis J. B., Mingioli E. S. 1950; Mutants of E. coli requiring methionine or vitamin B 12. J. Bact. 60:17
    [Google Scholar]
  11. Davis J. E., Strauss J. H. Jr., Sinsheimer R. L. 1961; Bacteriophage MS2: another RNA phage. Science, N. Y. 134:1427
    [Google Scholar]
  12. Dettori R., Maccacaro G. A., Piccinin G. L. 1961; Sex-specific bacteriophages of Escherichia coli k 12. G. Microbiol. 9:141
    [Google Scholar]
  13. Duguid J. P., Anderson E. S., Campbell I. 1966; Fimbriae and adhesive properties in Salmonellae. J. Path. Bact. 92:107
    [Google Scholar]
  14. Duguid J. P., Smith I. W., Dempster G., Edmunds P. N. 1955; Non-flagellar filamentous appendages (‘fimbriae’) and haemagglutinating activity in Bacterium coli . J. Path. Bact 70:335
    [Google Scholar]
  15. Egawa R., Hirota Y. 1962; Inhibition of fertility by the resistance factor (R) in Escherichia coli k-12. Jap. J. Genet. 37:66
    [Google Scholar]
  16. Harada K., Kameda M., Suzuki M., Mitsuhashi S. 1964; Drug resistance of enteric bacteria. III. Acquisition of transferability of nontransmissible R (TC) factor in cooperation with F factor and formation of FR (TC). J. Bact. 88:1257
    [Google Scholar]
  17. Hirota Y. 1960; The effect of acridine dyes on mating type in Escherichia coli . Proc. natn. Acad. SciU.S.A 4657
    [Google Scholar]
  18. Hirota Y., Sneath P. H. A. 1961; F′ and F-mediated transduction in Escherichia coli k-12. Jap. J. Genet. 36:307
    [Google Scholar]
  19. Hirota Y., Fujii T., Nishimura Y. 1966; Loss and repair of conjugal fertility and infectivity of the resistance factor and sex factor in Escherichia coli . J. Bact. 91:1298
    [Google Scholar]
  20. Hirota Y., Nishimura Y., Ørskov F., Ørskov I. 1964; Effect of drug-resistance factor R on the F properties of Escherichia coli . J. Bact. 87:341
    [Google Scholar]
  21. Hofschneider P. H. 1963; Untersuchungen über ‘Kleine’ E. coli k-12 Bakteriophagen. Z. Naturf 18b:203
    [Google Scholar]
  22. Ishibashi M. 1967; F pilus as f + antigen. J. Bact. 93:379
    [Google Scholar]
  23. Jacob F., Monod J. 1961; Genetic regulatory mechanisms in synthesis of proteins. J. molec. Biol 3:318
    [Google Scholar]
  24. Jacob F., Brenner S., Cuzin F. 1963; On the regulation of DNA replication in bacteria. Cold Spring Harb. Symp. quant. Biol 38329
    [Google Scholar]
  25. Lederberg J. 1947; Gene recombination and linked segregation in Escherichia coli . Genetics 3a:505
    [Google Scholar]
  26. Lederberg J., Lederberg E. M. 1956; Infection and heredity. In Cellular Mechanisms in Differentiation and Growth Rudnick D. 101 Princeton, N.J.: Princeton University Press;
    [Google Scholar]
  27. Lennox E. S. 1955; Transduction of linked genetic characters of the host by bacteriophage P1. Virology 1:190
    [Google Scholar]
  28. Loeb T., Zinder N. D. 1961; A bacteriophage containing RNA. Proc. natn. Acad. SciU.S.A 47282
    [Google Scholar]
  29. Maccacaro G. A., Colombo C., Nardo A. di. 1959; Studi sulle fimbrie batteriche, I. Lo studio genetico delle fimbrie. G. Microbiol. 7:1
    [Google Scholar]
  30. Meynell E., Datta N. 1966; The relation of resistance transfer factors to the F factor (sex factor) of Escherichia coli k-12. Genet. Res. 7:134
    [Google Scholar]
  31. Nishimura Y. 1964; Defective mutations of sex compatibility in Escherichia coli . Jap. J. Genet. 39:360
    [Google Scholar]
  32. Ochiai K. T., Yamanaka T., Kimura K., Sawada O. 1959; Studies on transfer of drug resistance between Shigella strains and Escherichia coli strains. Jap. J. med. Sci. Biol186134
    [Google Scholar]
  33. Stocker B. A. D., Zinder N. D., Lederberg J. 1953; Transduction of flagellar characters in Salmonella. J. gen. Microbiol. 9:410
    [Google Scholar]
  34. Sugino Y., Hirota Y. 1962; Conjugal fertility associated with resistance factor R in Escherichia coli . J. Bact. 84:902
    [Google Scholar]
  35. Valentine R. C., Strand M. 1965; Complexes of F-pili and RNA bacteriophage. Science, N. Y 148:511
    [Google Scholar]
  36. Watanabe T., Fukasawa T. 1961; Episome mediated transfer of drug resistance in Enterobacteriaceae III. Transduction of resistance factors. J. Bact. 82:202
    [Google Scholar]
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