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Abstract
SUMMARY: Cultures of Escherichia coli b which had received pretreatment with dihydrostreptomycin were considered to consist of two subpopulations corresponding to the two fractions of culture samples that did and did not survive through plating and incubation to produce visible colonies. No initial assumptions were made about the viability of the subpopulations at the time that the samples were taken. A general-purpose analogue computer was then used both in mathematical analysis and mathematical synthesis to investigate the growth characteristics of the survivors and non-survivors as functions both of time and of pretreatment.
- Accepted:
- Published Online:
© Society for General Microbiology 1967