1887

Abstract

SUMMARY

penicillinase plasmid diploids of the type (. ip /.ipC), when constructed in strain 147, normally segregated one of the two parental genotypes at a frequency of about 1/5000 divisions, and recombinants were rare. In about 2% of the diploid clones, however, segregation occurred at a much higher frequency and in these clones both plasmids might be lost together. Examination of these ‘unstable’ diploids suggests that their two plasmids are associated to form a single structure, so that they are subsequently lost or transduced together. The ease of formation of associated diploids suggests that the penicillinase plasmids may be circular.

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/content/journal/micro/10.1099/00221287-46-1-85
1967-01-01
2024-04-24
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