
Full text loading...
Staphylococcus aureus penicillinase plasmid diploids of the type (α. i+p+ A/β.i–pC+), when constructed in strain 147, normally segregated one of the two parental genotypes at a frequency of about 1/5000 divisions, and recombinants were rare. In about 2% of the diploid clones, however, segregation occurred at a much higher frequency and in these clones both plasmids might be lost together. Examination of these ‘unstable’ diploids suggests that their two plasmids are associated to form a single structure, so that they are subsequently lost or transduced together. The ease of formation of associated diploids suggests that the penicillinase plasmids may be circular.
Article metrics loading...
Full text loading...
References
Data & Media loading...