@article{mbs:/content/journal/micro/10.1099/00221287-45-1-83, author = "Bradley, D. E.", title = "The Structure and Infective Process of a Pseudomonas Aeruginosa Bacteriophage Containing Ribonucleic Acid", journal= "Microbiology", year = "1966", volume = "45", number = "1", pages = "83-96", doi = "https://doi.org/10.1099/00221287-45-1-83", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-45-1-83", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "SUMMARY: The electron microscope shows that there are a number of different morphological types of bacteriophages which grow on Pseudomonas aeruginosa. Some are conventional ones with contractile or non-contractile tails, but the most interesting is a tail-less phage containing RNA. The structure of both conventional and RNA phages is described. It is shown that the RNA phage probably infects the cell via polar pili. Intracellular multiplication and lysis by the RNA phage is followed in thin sections of infected cells. In the early stages, the nuclear region is much reduced and dense granular areas appear. These subsequently differentiate into crystalline aggregates of virus particles; at the same time a large bulge, identical to that found associated with spheroplast formation, appears. The crystals continue to increase in size until the spheroplast ruptures and lysis occurs.", }