1887

Abstract

SUMMARY: There is evidence that oxidation of -cresol by proceeds through 3-methylcatechol and 2-hydroxy-6-oxohepta-2,4-dienoic acid. 3-Methylcatechol has been characterized as a metabolite in growing cultures, and is oxidized by cells or cell extracts obtained from cultures grown on -cresol but not by those grown on glucose. The rates of dissimilation of 2-hydroxy-6-oxohepta-2,4-dienoic acid are in excess of its rates of formation from 3-methylcatechol by extracts of cells. The catechol 2,3-oxygenase is formed in response to a variety of inducers and will cleave the ring of catechol and 4-methylcatechol also. The low specificity of the 2,3-oxygenase and earlier enzymic activities (hydroxylases), to both inducers and substrates, is discussed.

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/content/journal/micro/10.1099/00221287-44-2-221
1966-08-01
2021-10-28
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References

  1. Bassham J. A., Calvin M. 1957 The Path of Carbon in Photosynthesis. Englewood Cliffs N. J. U.S.A.: Prentice-Hall.;
    [Google Scholar]
  2. Dagley S., Patel M. D. 1957; Oxidation of p-cresol and related compounds by a Pseudomonas.. Biochem. J. 66:227
    [Google Scholar]
  3. Dagley S., Evans W. C., Ribbons D. W. 1960; New pathways in the oxidative metabolism of aromatic compounds by micro-organisms.. Nature, Lond. 188:560
    [Google Scholar]
  4. Dagley S., Chapman P. J., Gibson D. T., Wood J. M. 1964; Degradation of the benzene nucleus by bacteria.. Nature, Lond. 202:775
    [Google Scholar]
  5. Evans W. C. 1947; Oxidation of phenol and benzoic acid by some soil bacteria.. Biochem. J. 41:373
    [Google Scholar]
  6. Evans W. C., Fernley H. N., Griffiths E. 1965; Oxidative metabolism of phenanthrene and anthracene by soil pseudomonads.. Biochem. J. 95:819
    [Google Scholar]
  7. Friedemann T. E., Haugen G. 1943; Pyruvic acid. II. The determination of keto acids in blood and urine.. J. biol. Chem. 147:415
    [Google Scholar]
  8. Gunsalus I. C., Chapman P. J., Kuo W. J. F. 1965; Control of catabolic specificity and metabolism.. Biochem. Biophys. Res. Comm. 18:924
    [Google Scholar]
  9. Ichihara A., Adachi K., Hosokawa K., Takeda Y. 1962; The enzymatic hydroxylation of aromatic carboxylic acids; substrate specificities of anthranilate and benzoate oxidases.. J. biol. Chem. 237:2296
    [Google Scholar]
  10. Kitagawa M. 1956; Studies on the oxidation mechanism of methyl group.. J. Biochem. 43:553
    [Google Scholar]
  11. Leibnitz E., Behrens U., Streigler G., Gabert A. 1962; Zur mikrobiellen Oxydation der p-ständigen Methylgruppe in Xylenolen. Z.. allg. Mikrobiol 2:81
    [Google Scholar]
  12. Nakagawa H., Inoue H., Takeda Y. 1963; Characteristics of catechol oxygenase from Brevibacterium fuscum.. J. Biochem. 54:65
    [Google Scholar]
  13. Pankhurst E. S. 1959; The biological oxidation of spent gas liquor.. J. appl. Bact 22:202
    [Google Scholar]
  14. Ribbons D. W. 1964; Bacterial metabolism of o-cresol.. Proc. 6th int. Congr. Biochem.
    [Google Scholar]
  15. Rogofe M. H., Wender I. 1957; Methylnaphthalene oxidations by pseudomonads.. J. Bact. 77:783
    [Google Scholar]
  16. Stanier R. Y. 1950; Problems of bacterial oxidative metabolism.. Bact. Rev. 14:179
    [Google Scholar]
  17. Treccanni V. 1963; The bacterial metabolism of hydrocarbons.. Prog. indust. Microbiol. 3:3
    [Google Scholar]
  18. Umbarger E., Davis B. D. 1962; Pathways of amino acid biosynthesis.. The Bacteria. Ed. by Gunsalus I. C., Stanier R. Y. 3167 New York: Academic Press.;
    [Google Scholar]
  19. Umbreit W. W., Burris R. H., Stauffer J. F. 1957 Manometric Techniques, 3rd. edn. Minneapolis, Minn., U.S.A.: Burgess Publishing Co.;
    [Google Scholar]
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