Extracts of cultures made with 0.01 N-HCI gave a precipitin reaction with type antisera. With 0.05 N-HCI, however, some cultures gave inactive extracts. Part of the type-specific polysaccharide is converted by the strong acid to a form in which it does not precipitate with homologous sera, but which specifically inhibits the reaction between antibody and unaltered antigen.


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