The Sterol Requirement of Free

Abstract

SUMMARY: Several sterols and related substances were tested for ability to promote sexual reproduction in These compounds were classified as (oospores formed), (oogonia and antheridia formed, but no oospores), or (no oogonia). Quantitative differences between active substances were noted in respect of the numbers of oospores produced and the time of their appearance. The most active substances tested were 29-isofucosterol and β-sitosterol. Loss of activity was associated with shortening of the side chain of the sterol molecule or change in its configuration, absence of a double bond in the B ring or of a hydroxyl group at position 3 on the A ring.

Loading

Article metrics loading...

/content/journal/micro/10.1099/00221287-42-3-425
1966-03-01
2024-03-29
Loading full text...

Full text loading...

References

  1. Clayton R. B., Bloch R. 1963; Sterol utilization in the hide beetle. Dermestes vulpinus. J. biol. Chem 238:586
    [Google Scholar]
  2. Elliott C. G., Hendrie M. R., Knights B. A., Pakker W. 1964; A steroid growth factor requirement in a fungus. Nature, Lond 203:427
    [Google Scholar]
  3. Harnish W. N., Berg L. A., Lilly V. G. 1964; Factors in lima bean and hemp seed required for oospore formation by species of Phytophthora. Phytopathology 54:895
    [Google Scholar]
  4. Haskins R. H., Tulloch A. P., Micetich R. G. 1964; Steroids and the stimulation of sexual reproduction of a species of Pythium. Canad. J. Microbiol 10:187
    [Google Scholar]
  5. Hendrix J. W. 1964; Sterol induction of reproduction and stimulation of growth of Pythium and Phytophthora. Science 144:1028
    [Google Scholar]
  6. Hendrix J. W. 1965; Influence of sterols on growth and reproduction of Pythium and Phytophthora spp. Phytopathology 55:790
    [Google Scholar]
  7. Holz G. G., Erwin J., Rosenbaum N., Aaronson S. 1962; Triparanol inhibition of Tetrahymena, and its prevention by lipids. Arch. Biochem. Biophys 98:312
    [Google Scholar]
  8. Holz G. G., Wagner G., Erwin J., Britt J. J., Bloch R. 1961; Sterol requirements of a ciliate, Tetrahymena corlissi Th-X. Comp. Biochem. Physiol. 2 202:
    [Google Scholar]
  9. Knights B. A. 1965; Identification of the sterols of oat seed. Phytochemistry 4:857
    [Google Scholar]
  10. Leal J. A., Friend J., Holliday P. 1964; A factor controlling sexual reproduction in Phytophthora. Nature, Lond 203:545
    [Google Scholar]
  11. Smith P. F., Lynn R. J. 1958; Lipid requirements for the growth of pleuropneumonia-like organisms. J. Bact 76:264
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journal/micro/10.1099/00221287-42-3-425
Loading

Most cited Most Cited RSS feed