@article{mbs:/content/journal/micro/10.1099/00221287-42-2-245, author = "AVERNER, M. and FULTON, C.", title = "Carbon dioxide: Signal for Excystment of Naegleria gruberi", journal= "Microbiology", year = "1966", volume = "42", number = "2", pages = "245-255", doi = "https://doi.org/10.1099/00221287-42-2-245", url = "https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-42-2-245", publisher = "Microbiology Society", issn = "1465-2080", type = "Journal Article", abstract = "SUMMARY: Exposure of cysts of Naegleria gruberi to slightly increased environmental CO2 caused excystement. Excystment was also induced by addition of proline or by an increase in the cyst population density, but both did so by increasing the amount of CO2 produced by the bacteria (Aerobacter aerogenes) which contaminated the cyst suspensions. Molecular CO2 would seem to be an excellent signal to induce excystment of a phagotrophic soil amoeba since the presence of CO2 would indicate an environment favourable for growth of the amoebae. Once excystment is initiated, it can proceed to completion in atmospheric CO2.", }